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Xi¡¯an Spring-chem Bio-tech Co., Ltd

Products >> Supply: Paclitaxel

Supply: Paclitaxel

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Description
Product Name: Supply: Paclitaxel
Supply Ability: 10Kg
Related proudcts
Specifications 99%
Price Term: FOB
Port of loading: Shanghai
Minimum Order 100g
Unit Price: 700

Paclitaxel

Product Name: Paclitaxel
Botanical source: Taxaceae
CAS NO: 33069-62-4
Molecular formula: C47H51NO14
Systematic (IUPAC) name:
¦Â-(benzoylamino)-¦Á-hydroxy-,6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-ylester,(2aR-(2a-¦Á,4-¦Â,4a-¦Â,6-¦Â,9-¦Á(¦Á-R*,¦Â-S*),11-¦Á,12-¦Á,12a-¦Á,2b-¦Á))-benzenepropanoic acid
Specification: Paclitaxel >99% 90% 3%
Sieve analysis: 100% through 100 mesh
Residue on ignition: 1.0%
Residual Solvents: Eur.Pharm.
Heavy metals: <10PPM
Pesticides: Negative
Total Plate Count:<1000CFU/gm
Yeast & Mold:<100CFU/gm
Salmonella: Negative
E.Coli: Negative
Storage: Store in cool & dry place, Keep away from strong light and heat.
Shelf life: 24 Months when properly stored.
Packing: Paper-drums and two plastic-bags inside
N.W.: 5kg
INDICATIONS:
Paclitaxel is a mitotic inhibitor drug used in the treatment of cancer. It was discovered at Research Triangle Institute (RTI) in 1967 when Monroe E. Wall and Mansukh C. Wani isolated the compound from the bark of the Pacific yew tree, Taxus brevifolia, and noted its antitumor activity in a broad range of rodent tumors. By 1970, the two scientists had ***ermined the structure of paclitaxel. Paclitaxel has since become an effective tool of ***tors who treat patients with lung, ovarian, breast cancer, and advanced forms of Kaposi's sarcoma.[2] It is sold under the tradename Taxol. Together with ***etaxel, it forms the drug category of the taxanes.
Paclitaxel is also used for the prevention of restenosis (recurrent narrowing) of coronary stents; locally delivered to the wall of the coronary artery, a paclitaxel coating limits the growth of neointima (scar tissue) within stents.[3] Paclitaxel drug eluting coated stents are sold under the trade name Taxus by Boston Scientific in the United States.

Contact Us
Company: Xi¡¯an Spring-chem Bio-tech Co., Ltd
Contact: Mr. He Wenbin
Address: Mingde Jingyuan Building, Zhuque Street,Yanta District , Xi¡¯an China
Postcode: 710100
Tel: 86 29 68800245
Fax: 86-029-85657461
E-mail:         


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